Ecto-ADP-Ribosyltransferase 4 (ART4) Antibody
260€ (50 µl)
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935106861
info@markelab.com
name
Ecto-ADP-Ribosyltransferase 4 (ART4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx210396
tested applications
ELISA, WB, IHC
Description
ART4 Antibody is a Rabbit Polyclonal against ART4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ecto-ADP-Ribosyltransferase 4 (ART4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/2000 - 1/10000, WB: 1/1000 - 1/5000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q93070 |
| Gene ID | 420 |
| Alias | ADP-ribosyltransferase C2 and C3 toxin-like 4,Dombrock blood group,DO,DOK1,ARTC4,CD297,DO/ART4,Ecto-ADP-ribosyltransferase 4,Mono(ADP-ribosyl)transferase 4 |
| Background | Antibody anti-ART4 |
| Status | RUO |
Descripción
ADP-ribosyltransferase 4 (ART4), also known as CD297, is an enzyme that belongs to the ART family of ADP-ribosyltransferases. These enzymes mediate the transfer of ADP-ribose from NAD+ (nicotinamide adenine dinucleotide) to specific target proteins, a modification that alters their functions. ADP-ribosylation is a post-translational modification that can impact a variety of cellular processes, such as signaling, immune regulation, and cell differentiation. ART4 is a GPI-anchored ectoenzyme, meaning it is attached to the outer surface of the plasma membrane and targets extracellular proteins. ART4 is particularly known for its association with the Dombrock (Do) blood group system, where variations in ART4 contribute to antigenic diversity on red blood cells. Its functions and expression are implicated in immune cell regulation, and it has been investigated for potential roles in immune and hematologic disorders.
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