Rat Activin A Receptor Type 2B (ACVR2B) Protein
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935106861
info@markelab.com
Precio
2275€ (1 mg)
Protein ACVR2B
proveedor
Abbexareference
abx065143Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Activin A Receptor Type II B (ACVR2B) is a recombinant Rat protein produced in E. coli using Prokaryotic expression.
Background
ACVR2B is another type II receptor involved in activin and myostatin signaling pathways. It phosphorylates type I receptors (e.g., ACVR1B) to activate SMAD-dependent signaling cascades. ACVR2B regulates processes like muscle growth, reproductive function, and embryonic development. Inhibition of ACVR2B has been explored as a therapeutic approach for muscle-wasting disorders, such as cachexia and muscular dystrophy. Mutations in ACVR2B can impair ligand-receptor interactions, leading to developmental defects.
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Activin A Receptor Type 2B (ACVR2B)
host
E. coli
conjugation
Unconjugated
form
Lyophilized
tested applications
WB, SDS-PAGE
size 1
1 mg
size 2
5 mg
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ACVR2B
dry ice
No
availability
Shipped within 1-2 months.
alias
Activin receptor type IIB,ACTR-IIB
uniprot id
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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