Activin A Receptor Type 2B (ACVR2B) Antibody
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935106861
info@markelab.com
Precio
175€ (20 µl)
Antibody anti-ACVR2B
proveedor
Abbexareference
abx007082Tested Applications
WB, IF/ICCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
ACVR2B Antibody is a Rabbit Polyclonal Antibody against ACVR2B.
Background
ACVR2B is another type II receptor involved in activin and myostatin signaling pathways. It phosphorylates type I receptors (e.g., ACVR1B) to activate SMAD-dependent signaling cascades. ACVR2B regulates processes like muscle growth, reproductive function, and embryonic development. Inhibition of ACVR2B has been explored as a therapeutic approach for muscle-wasting disorders, such as cachexia and muscular dystrophy. Mutations in ACVR2B can impair ligand-receptor interactions, leading to developmental defects.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Activin A Receptor Type 2B (ACVR2B)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
WB, IF/ICC
purification
Purified by affinity chromatography.
buffer
PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
size 1
20 µl
size 2
50 µl
size 3
100 µl
size 4
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ACVR2B
dry ice
No
availability
Shipped within 5-10 working days.
alias
Activin receptor type IIB,ACTR-IIB
uniprot id
NCBI accession
NP_001097.2
note
This product is for research use only.
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