Rat Activin A Receptor Type 1B (ACVR1B) Protein
![Rat Activin A Receptor Type 1B (ACVR1B) Protein](/_next/image?url=https%3A%2F%2Fmarkelab.com%2Fpublic-files%2Fimages%2FAntibody-Box.png&w=3840&q=75)
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935106861
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Precio
837.5€ (100 µg)
Protein ACVR1B
proveedor
Abbexareference
abx691050Tested Applications
SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat ACVR1B Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat ACVR1B (Met1-Glu126) was expressed with the Fc region of human IgG1 at the C-terminus.
Background
ACVR1B, also known as ALK4, is a type I receptor primarily activated by activins, inhibins, and Nodal ligands. This receptor phosphorylates SMAD2/3 to propagate downstream signaling, which regulates cellular processes such as differentiation, proliferation, and embryonic patterning. ACVR1B is expressed in many tissues, particularly during early development. Mutations in ACVR1B have been associated with tumorigenesis and reproductive disorders due to its role in cell cycle regulation and tissue homeostasis.
Características del producto
category
Proteins and Peptides
origin
Rat
host
HEK293 cells
immunogen target
ACVR1B
host
HEK293 cells
tested applications
SDS-PAGE
size 1
100 µg
expression
Recombinant
purity
> 95% (SDS-PAGE)
buffer
Lyophilized from sterile PBS, pH 7.4.
storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
or code
ACVR1B
dry ice
No
availability
Shipped within 5-15 working days.
alias
ACTR-IB,ALK-4,Serine/threonine-protein kinase receptor R2 (SKR2)
NCBI accession
NP_954700.1
note
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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