Rat Activin A Receptor Type 1B (ACVR1B) Protein

Este producto es parte de ACVR - Activin A Receptor Type
Rat Activin A Receptor Type 1B (ACVR1B) Protein

Pida mas información

935106861

info@markelab.com

Precio

837.5€ (100 µg)

Protein ACVR1B

proveedor

Abbexa

reference

abx691050

Tested Applications

SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat ACVR1B Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat ACVR1B (Met1-Glu126) was expressed with the Fc region of human IgG1 at the C-terminus.


Background

ACVR1B, also known as ALK4, is a type I receptor primarily activated by activins, inhibins, and Nodal ligands. This receptor phosphorylates SMAD2/3 to propagate downstream signaling, which regulates cellular processes such as differentiation, proliferation, and embryonic patterning. ACVR1B is expressed in many tissues, particularly during early development. Mutations in ACVR1B have been associated with tumorigenesis and reproductive disorders due to its role in cell cycle regulation and tissue homeostasis.

Características del producto

category

Proteins and Peptides


origin

Rat


host

HEK293 cells


immunogen target

ACVR1B


host

HEK293 cells


tested applications

SDS-PAGE


size 1

100 µg


expression

Recombinant


purity

> 95% (SDS-PAGE)


buffer

Lyophilized from sterile PBS, pH 7.4.


storage

Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.


or code

ACVR1B


dry ice

No


availability

Shipped within 5-15 working days.


alias

ACTR-IB,ALK-4,Serine/threonine-protein kinase receptor R2 (SKR2)


NCBI accession

NP_954700.1


note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.


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