Rat Activin A Receptor Type 1B (ACVR1B) Protein (Active)

Este producto es parte de ACVR - Activin A Receptor Type
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1079€ (100 µg)

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935106861
info@markelab.com
name
Rat Activin A Receptor Type 1B (ACVR1B) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx691050
tested applications
SDS-PAGE

Description

Rat ACVR1B Protein is a recombinant protein from Rat produced in HEK293 Cells. A DNA sequence encoding the rat ACVR1B (Met1-Glu126) was expressed with the Fc region of human IgG1 at the C-terminus.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
ACVR1B
Host
HEK293 cells
Origin
Rat
Observed MW
Molecular Weight: 38.4 kDa
Sequence Fragment: Met1-Glu126
Tag: C-terminal Fc tag
Validity: The validity for this protein is 12 months.
Expression
Recombinant
Purity
> 95% (SDS-PAGE)
Size 1
100 µg
Form
 
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
NP_954700.1
Alias
ACTR-IB,ALK-4,Serine/threonine-protein kinase receptor R2 (SKR2)
Background
Protein ACVR1B
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ACVR1B, also known as ALK4, is a type I receptor primarily activated by activins, inhibins, and Nodal ligands. This receptor phosphorylates SMAD2/3 to propagate downstream signaling, which regulates cellular processes such as differentiation, proliferation, and embryonic patterning. ACVR1B is expressed in many tissues, particularly during early development. Mutations in ACVR1B have been associated with tumorigenesis and reproductive disorders due to its role in cell cycle regulation and tissue homeostasis.

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