Rat Actinin Alpha 1 (ACTN1) Protein
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935106861
info@markelab.com
Precio
208€ (10 µg)
Protein ACTN1
proveedor
Abbexareference
abx655895Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Rat ACTN1 Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).
Background
ACTN1 encodes alpha-actinin-1, a member of the actin-binding protein family that plays a key role in cytoskeletal organization and cellular architecture. It is primarily expressed in non-muscle cells, where it functions as a crosslinker of actin filaments and regulates the assembly of the actin cytoskeleton. ACTN1 is involved in diverse cellular processes such as cell adhesion, migration, and signaling, contributing to tissue integrity and dynamic cellular responses. It is also implicated in the regulation of focal adhesions and mechanotransduction. Mutations in ACTN1 have been associated with autosomal dominant macrothrombocytopenia, characterized by abnormally large platelets and reduced platelet count, highlighting its role in platelet formation and function. Its interaction with actin filaments and various signaling proteins underscores its importance in maintaining cellular stability and enabling dynamic cellular behaviors.
Características del producto
category
Proteins and Peptides
origin
Rat
host
E. coli
immunogen target
Actinin Alpha 1 (ACTN1)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 30.1 kDa Observed MW (SDS-PAGE): 30 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ala28-Asn260 Tag: N-terminal His tag
expression
Recombinant
purity
> 90%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
ACTN1
dry ice
No
availability
Shipped within 5-7 working days.
alias
BDPLT15
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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