Rat Actinin Alpha 1 (ACTN1) Protein

Este producto es parte de ACTN - Actinin Alpha
Rat Actinin Alpha 1 (ACTN1) Protein

Pida mas información

935106861

info@markelab.com

Precio

208€ (10 µg)

Protein ACTN1

proveedor

Abbexa

reference

abx655895

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rat ACTN1 Protein is a recombinant Rat protein produced in a Prokaryotic expression system (E. coli).


Background

ACTN1 encodes alpha-actinin-1, a member of the actin-binding protein family that plays a key role in cytoskeletal organization and cellular architecture. It is primarily expressed in non-muscle cells, where it functions as a crosslinker of actin filaments and regulates the assembly of the actin cytoskeleton. ACTN1 is involved in diverse cellular processes such as cell adhesion, migration, and signaling, contributing to tissue integrity and dynamic cellular responses. It is also implicated in the regulation of focal adhesions and mechanotransduction. Mutations in ACTN1 have been associated with autosomal dominant macrothrombocytopenia, characterized by abnormally large platelets and reduced platelet count, highlighting its role in platelet formation and function. Its interaction with actin filaments and various signaling proteins underscores its importance in maintaining cellular stability and enabling dynamic cellular behaviors.

Características del producto

category

Proteins and Peptides


origin

Rat


host

E. coli


immunogen target

Actinin Alpha 1 (ACTN1)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 30.1 kDa Observed MW (SDS-PAGE): 30 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ala28-Asn260 Tag: N-terminal His tag


expression

Recombinant


purity

> 90%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

ACTN1


dry ice

No


availability

Shipped within 5-7 working days.


alias

BDPLT15


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


Quizá le pueda interesar

Human ACTN1(Alpha-actinin-1) ELISA Kit

Human ACTN1(Alpha-actinin-1) ELISA Kit

proveedor

FineTest

reference

EH4480

reactivity

human

status

RUO

Precio a consultar

Ver más

anti- alpha Actinin antibody

anti- alpha Actinin antibody

proveedor

FineTest

reference

FNab00322

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse,rat,monkey

status

RUO

clonality

polyclonal

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, includ...

Precio a consultar

Ver más

Recombinant Human ACTN1

Recombinant Human ACTN1

proveedor

FineTest

reference

P0573

Tested Applications

Western Blot, ELISA

status

RUO

Precio a consultar

Ver más