Rat Actinin Alpha 1 (ACTN1) Protein

Este producto es parte de ACTN - Actinin Alpha
Rat Actinin Alpha 1 (ACTN1) Protein
208€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Rat Actinin Alpha 1 (ACTN1) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx655895
Tested Applications
WB, SDS-PAGE

Description

Rat ACTN1 Protein is a recombinant Rat protein expressed in E. coli.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Actinin Alpha 1 (ACTN1)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Ala28-Asn260
Tag: N-terminal His tag
Origin
Rat
Conjugation
Unconjugated
Observed MW
Calculated MW: 30.1 kDa  Observed MW (SDS-PAGE): 30 kDa
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
Q9Z1P2
Gene ID
81634
Alias
BDPLT15
Background
Protein ACTN1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Background

ACTN1 encodes alpha-actinin-1, a member of the actin-binding protein family that plays a key role in cytoskeletal organization and cellular architecture. It is primarily expressed in non-muscle cells, where it functions as a crosslinker of actin filaments and regulates the assembly of the actin cytoskeleton. ACTN1 is involved in diverse cellular processes such as cell adhesion, migration, and signaling, contributing to tissue integrity and dynamic cellular responses. It is also implicated in the regulation of focal adhesions and mechanotransduction. Mutations in ACTN1 have been associated with autosomal dominant macrothrombocytopenia, characterized by abnormally large platelets and reduced platelet count, highlighting its role in platelet formation and function. Its interaction with actin filaments and various signaling proteins underscores its importance in maintaining cellular stability and enabling dynamic cellular behaviors.

Productos relacionados

abx001074

Alpha Actinin 1 (ACTN1) Antibody

ACTN1 Antibody is a Rabbit Polyclonal antibody against ACTN1. Alpha actinins belong to the spectrin gene superfamily whi…

Ver producto
abx013891

Alpha Actinin 1 (ACTN1) Antibody

Rabbit polyclonal antibody against ACTN1 protein. Immunogen region is N-terminal.…

Ver producto
abx013893

ACTN1 / 2 / 3 / 4 Antibody

Rabbit polyclonal antibody against ACTN1/2/3/4 protein. Immunogen region is N-terminal.…

Ver producto