Rat 3-Ketoacyl-CoA Thiolase, Mitochondrial (ACAA2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ACAA2
proveedor
Abbexareference
abx549584Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat 3-Ketoacyl-CoA Thiolase, Mitochondrial (ACAA2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat 3-Ketoacyl-CoA Thiolase, Mitochondrial concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Acetyl Coenzyme A Acyltransferase 2 (ACAA2), also known as mitochondrial 3-ketoacyl-CoA thiolase, is an essential mitochondrial enzyme involved in the beta-oxidation of fatty acids. It catalyzes the thiolytic cleavage of 3-ketoacyl-CoA into acetyl-CoA, which then enters the TCA cycle for ATP production. ACAA2 is highly expressed in energy-demanding tissues such as the liver, heart, and muscle, where it plays a key role in maintaining metabolic flexibility and energy production during fasting or exercise. Mutations or deficiencies in ACAA2 can impair mitochondrial fatty acid oxidation, leading to conditions such as mitochondrial fatty acid oxidation disorders and myopathies. Beyond its metabolic role, ACAA2 activity influences reactive oxygen species (ROS) production and mitochondrial dynamics, linking it to cellular stress responses and metabolic regulation. Ongoing research explores its potential as a therapeutic target for metabolic diseases and mitochondrial dysfunction.
Características del producto
category
ELISA Kits
immunogen target
3-Ketoacyl-CoA Thiolase, Mitochondrial (ACAA2)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
DSAEC
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACAA2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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