Rat Acetyl Coenzyme A Acetyltransferase 2 (ACAT2) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ACAT2
proveedor
Abbexareference
abx549575Tested Applications
ELISAreactivity
Ratstatus
RUOclonality
Descripción
Rat Acetyl Coenzyme A Acetyltransferase 2 (ACAT2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Acetyl-CoA acetyltransferase, cytosolic concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACAT2 is a cytosolic enzyme that is primarily expressed in the liver and intestine and is responsible for the esterification of cholesterol with long-chain fatty acids to form cholesteryl esters, which are then incorporated into lipoproteins such as very-low-density lipoproteins (VLDL) and chylomicrons. Unlike ACAT1, which is involved in mitochondrial ketone metabolism, ACAT2 plays a pivotal role in cholesterol homeostasis and lipid transport. It is essential for the packaging of cholesterol for transport through the bloodstream and is therefore crucial for maintaining lipid balance. Dysregulation of ACAT2 activity is associated with hypercholesterolemia and atherosclerosis, as increased cholesteryl ester formation can contribute to the formation of atherosclerotic plaques. Targeting ACAT2 has been explored as a potential therapeutic approach for reducing cholesterol levels and cardiovascular disease risk.
Características del producto
category
ELISA Kits
immunogen target
Acetyl Coenzyme A Acetyltransferase 2 (ACAT2)
reactivity
Rat
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
ACAT2,Sterol O-acyltransferase 2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACAT2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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