Rat Acadm (Medium-chain specific acyl-CoA dehydrogenase, mitochondrial) ELISA Kit
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Name
Rat Acadm (Medium-chain specific acyl-CoA dehydrogenase, mitochondrial) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
ER0422
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | 2 hours |
| Assay Type | Competitive ELISA, Coated with Antigen |
| Test Range | 0.781-50ng/ml |
| Sensitivity | 0.469ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P08503 |
| Alias | ACAD1,MCAD,MCADH |
| Background | Elisa kits for Acadm |
| Status | RUO |
Background
The ACADM gene encodes the enzyme acyl-Coenzyme A dehydrogenase, specific to medium-chain fatty acids (C4 to C12 straight chain). This enzyme plays a crucial role in the initial step of the mitochondrial fatty acid beta-oxidation pathway, essential for converting medium-chain fatty acids into energy, particularly during fasting periods. Defects in this gene lead to medium-chain acyl-CoA dehydrogenase deficiency, characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can be fatal in infants. ACADM enzyme functions within mitochondria, primarily in the liver, where it aids in the breakdown of medium-chain fatty acids obtained from diet or stored in the body's fat tissue. Alternative splicing generates various isoforms of this enzyme.
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