Rat Abhydrolase Domain Containing 12 (ABHD12) ELISA Kit
715€ (96 tests)
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935106861
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name
Rat Abhydrolase Domain Containing 12 (ABHD12) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx390915
tested applications
ELISA
Description
Rat Abhydrolase Domain Containing 12 (ABHD12) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Abhydrolase Domain Containing 12 (ABHD12) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Abhydrolase Domain Containing 12 (ABHD12) |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q6AYT7 |
| Gene ID | 499913 |
| Alias | ABHD12A,BEM46L2,C20orf22,PHARC |
| Background | Elisa kits for ABHD12 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABHD12 (Abhydrolase Domain Containing 12) is a membrane-bound serine hydrolase primarily involved in lipid metabolism and neuroinflammatory regulation. It plays a critical role in degrading lysophosphatidylserine (lyso-PS), a bioactive lipid mediator involved in immune signaling. ABHD12 is highly expressed in the brain and other tissues, where it regulates lipid signaling pathways crucial for neural function and homeostasis. Mutations in the ABHD12 gene are associated with PHARC syndrome (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataracts), a neurodegenerative disorder. This enzyme’s activity is essential for maintaining balanced lipid signaling and protecting against neuroinflammation and neurodegeneration.
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