Rat Abcc1 (Multidrug resistance-associated protein 1) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Rat Abcc1 (Multidrug resistance-associated protein 1) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
ER0431
tested applications
ELISA
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Reactivity | Rat |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q8CG09 |
| Alias | ABC29,ABCC,DFNA77,GS-X,MRP,MRP1 |
| Background | Elisa kits for Abcc1 |
| Status | RUO |
ABCC1, also known as multidrug resistance-associated protein 1 (MRP1), is a transmembrane ATP-binding cassette transporter that effluxes a wide range of substrates, including drugs, xenobiotics, and endogenous molecules such as glutathione, leukotrienes, and conjugated metabolites. It is highly expressed in barrier tissues, such as the blood-brain barrier, lungs, and liver, where it protects cells by exporting potentially toxic compounds. ABCC1 plays a key role in multidrug resistance, as its overexpression in cancer cells reduces the efficacy of chemotherapeutic agents by actively transporting them out of cells. Structurally, ABCC1 contains two transmembrane domains and two ATP-binding domains that enable ATP-driven substrate transport. Dysregulation of ABCC1 activity is implicated in various pathological conditions, including drug resistance, inflammation, and oxidative stress, making it a target for therapeutic intervention in oncology and pharmacology.
Related Products
