Rat 3-ketoacyl-CoA thiolase B, peroxisomal (ACAA1B) ELISA Kit

Este producto es parte de ACAA - Acetyl Coenzyme A Acyltransferase
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715€ (96 tests)

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935106861
info@markelab.com
name
Rat 3-ketoacyl-CoA thiolase B, peroxisomal (ACAA1B) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx549580
tested applications
ELISA

Description

Rat 3-ketoacyl-CoA thiolase B, peroxisomal (ACAA1B) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat 3-ketoacyl-CoA thiolase B, peroxisomal concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
3-ketoacyl-CoA thiolase B, peroxisomal (ACAA1B)
Reactivity
Rat
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P07871
Alias
RGD1562373
Background
Elisa kits for ACAA1B
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Acetyl Coenzyme A Acyltransferase 1B (ACAA1B) is a closely related isoform of ACAA1, sharing similar catalytic activity as a thiolase in the beta-oxidation of fatty acids within peroxisomes. ACAA1B is involved in cleaving 3-ketoacyl-CoA to generate acetyl-CoA, which can be used for energy production or other biosynthetic pathways. While its function overlaps significantly with ACAA1A, ACAA1B may have distinct tissue-specific expression patterns or substrate preferences, suggesting a specialized role in certain metabolic contexts. ACAA1B contributes to cellular energy homeostasis and lipid regulation and is essential for the detoxification of fatty acid intermediates. Defects in ACAA1B function can exacerbate peroxisomal disorders, leading to metabolic imbalances and systemic effects. Additionally, ACAA1B is being investigated for its role in metabolic diseases such as obesity and type 2 diabetes, where dysregulated fatty acid metabolism is a key factor. Further studies are needed to delineate the specific contributions of ACAA1B in health and disease.

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