Rat 14-3-3 Protein Eta (YWHAH) ELISA Kit

Este producto es parte de YWHAH - 14-3-3 protein eta
Rat 14-3-3 Protein Eta (YWHAH) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for YWHAH

proveedor

Abbexa

reference

abx500014

Tested Applications

ELISA

reactivity

Rat

status

RUO

clonality

Descripción

Rat 14-3-3 Protein Eta (YWHAH) ELISA Kit for the in vitro quantitative measurement of Rat 14-3-3 protein eta concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

YWHAH, a member of the 14-3-3 protein family, acts as an adaptor molecule that binds phosphorylated serine/threonine residues on target proteins, regulating their stability, localization, and function. YWHAH is highly expressed in the brain, where it is involved in synaptic plasticity, neurotransmitter release, and neuronal development. It interacts with key signaling molecules in pathways such as MAPK, PI3K/Akt, and dopamine receptor signaling, influencing cellular processes like survival, growth, and stress response. Dysregulation of YWHAH is associated with neurological disorders such as schizophrenia, Parkinson’s disease, and rheumatoid arthritis, where altered signaling contributes to disease pathogenesis. Elevated levels of YWHAH have been detected in autoimmune diseases, highlighting its role as a biomarker. Knockout studies demonstrate impaired synaptic transmission, defects in neuronal signaling, and altered stress adaptation, emphasizing its importance in brain function, neurodevelopment, and immune regulation.

Características del producto

category

ELISA Kits


immunogen target

14-3-3 Protein Eta (YWHAH)


reactivity

Rat


test range

0.156 ng/ml - 10 ng/ml


sensitivity

< 0.07 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

YWHAH, YWHA1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

YWHAH


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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