Ras/Rap Gtpase-Activating Protein Syngap (SYNGAP1) Antibody
260€ (50 µg)
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935106861
info@markelab.com
name
Ras/Rap Gtpase-Activating Protein Syngap (SYNGAP1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx456859
tested applications
ELISA, WB, IHC
Description
Ras/Rap Gtpase-Activating Protein Syngap (SYNGAP1) Antibody is a Rabbit polyclonal antibody for the detection of Human Ras/Rap Gtpase-Activating Protein Syngap (SYNGAP1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras/Rap Gtpase-Activating Protein Syngap (SYNGAP1) Immunogen: Recombinant Ras/Rap Gtpase-Activating Protein Syngap (Ser1186-His1277) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96PV0 |
| Gene ID | 8831 |
| NCBI Accession | NP_001123538.1 |
| Background | Antibody anti-SYNGAP1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits(By similarity).
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