SYNGAP1 antibody
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935106861
info@markelab.com
name
SYNGAP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab08437
tested applications
ELISA, WB, IF
Description
Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | synaptic Ras GTPase activating protein 1 homolog(rat) (SYNGAP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 148 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96PV0 |
| Gene ID | 8831 |
| Alias | Ras/Rap GTPase-activating protein SynGAP,Neuronal RasGAP,Synaptic Ras GTPase-activating protein 1 (Synaptic Ras-GAP 1),SYNGAP1,KIAA1938 |
| Background | Antibody anti-SYNGAP1 |
| Status | RUO |
| Note | Mol. Weight 148 kDa |
Descripción
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SYNGAP1 antibody
Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits(By similarity).
Ver Producto