Ras-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1) Antibody
195€ (20 µl)
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Name
Ras-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx005283
Tested Applications
ELISA, WB
Description
RASGRF1 Antibody is a Rabbit Polyclonal antibody against RASGRF1. The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1) Immunogen: Recombinant protein corresponding to RASGRF1. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Mouse |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 145 kDa Observed MW: 145 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13972 |
| Gene ID | 5923 |
| NCBI Accession | NP_001139120.1 |
| OMIM | 606600 |
| Background | Antibody anti-RASGRF1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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