Ras-Related Protein Rab-5A (Rab5) Antibody (HRP)
546€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Ras-Related Protein Rab-5A (Rab5) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx446101
Tested Applications
WB, IHC, IF/ICC
Description
Rab5 Antibody (HRP) is a Rabbit Polyclonal against Rab5.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ras-Related Protein Rab-5A (Rab5) Immunogen: Human Rab5 synthetic peptide conjugated to KLH; identical to dog Rab5 sequence over the residues |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat, Cow, Monkey |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/1000, IHC: 1/100, IF/ICC: 1/80. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Purification | Purified by Protein A. |
| Size 1 | 100 µg |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | PBS, 50% glycerol, 0.09% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at 4°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20339 |
| Gene ID | 5868 |
| NCBI Accession | NP_004153.2 |
| OMIM | 179512 |
| Alias | RAB5,Ras-related protein Rab-5A |
| Background | Antibody anti-RAB5A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB5A, member RAS oncogene family (RAB5A) is another member of the RAB family of small GTPases, playing a crucial role in regulating early endosome dynamics and vesicular trafficking RAB5A is involved in the initiation of endocytosis, controlling the fusion of early endosomes and the processing of internalized material It is essential for receptor-mediated endocytosis, where it helps sort and direct cargo for degradation or recycling within the cell RAB5A also participates in the regulation of cell signaling, including receptor tyrosine kinase signaling, and is involved in maintaining cellular communication and response to external signals Dysregulation of RAB5A activity has been linked to a variety of disorders, including cancer, where aberrant endosomal trafficking can influence tumor progression and metastasis Additionally, RAB5A plays a role in immune responses and the trafficking of immune receptors, further highlighting its importance in both normal cellular processes and disease pathogenesis
Productos relacionados
RAB5A, Member RAS Oncogene Family (RAB5A) Antibody
RAB5A Antibody is a Rabbit Polyclonal antibody against RAB5A. RAB5A (RAB5A, member RAS oncogene family) is a protein-cod…
Ver producto
Ras-Related Protein Rab-5A (Rab5) Antibody
Rab5 is required for the fusion of plasma membranes and early endosomes.…
Ver producto Ras-Related Protein Rab-5A (RAB5A) Antibody
Ras-related protein Rab-5A Antibody is a Rabbit Polyclonal antibody against Ras-related protein Rab-5A.…
Ver producto