Ras-related protein Rab-33B (RAB33B) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Ras-related protein Rab-33B (RAB33B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx240008
tested applications
ELISA, WB
Description
Ras-related protein Rab-33B (RAB33B) Antibody is a Rabbit Polyclonal antibody for the detection of RAB33B.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-related protein Rab-33B (RAB33B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H082 |
| Alias | SMC2,Ras-related protein Rab-33B |
| Background | Antibody anti-RAB33B |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
RAB33B, member RAS oncogene family (RAB33B) is a member of the RAB family of GTPases that regulates vesicular trafficking and cellular homeostasis RAB33B participates in the sorting and trafficking of proteins between the Golgi apparatus, endosomes, and lysosomes, playing an essential role in intracellular membrane dynamics It is particularly involved in the regulation of autophagy, where it aids in the formation and maturation of autophagosomes, which are responsible for the degradation of damaged or unnecessary cellular components In addition to its role in autophagy, RAB33B regulates the function of cellular membranes by influencing the movement of vesicles and cargo proteins between cellular compartments This is important for maintaining cellular signaling, protein recycling, and membrane dynamics RAB33B has also been implicated in modulating the immune response and cell migration, processes critical for tissue repair, inflammation, and cancer metastasis Dysregulation of RAB33B can lead to various diseases, including neurodegenerative disorders and cancers, where altered vesicular trafficking contributes to pathological changes in cellular function and behavior
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