Ras-Related Protein Rab-28 (RAB28) Antibody
169€ (20 µg)
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935106861
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name
Ras-Related Protein Rab-28 (RAB28) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx302115
tested applications
ELISA, IHC, IF/ICC
Description
RAB28 Antibody is a Rabbit Polyclonal against RAB28.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-Related Protein Rab-28 (RAB28) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P51157 |
| Gene ID | 9364 |
| NCBI Accession | NP_001017979.1, NM_001017979.2 |
| OMIM | 612994 |
| Alias | CORD18,Ras-related protein Rab-28 |
| Background | Antibody anti-RAB28 |
| Status | RUO |
Descripción
RAB28, member RAS oncogene family (RAB28) is involved in regulating vesicular trafficking, particularly in processes related to the transport of proteins and lipids between the Golgi apparatus, endosomes, and the plasma membrane RAB28 plays a key role in the sorting and recycling of membrane proteins, ensuring the proper function of cell surface receptors, which is essential for signal transduction and cellular homeostasis It is implicated in the regulation of autophagy and the degradation of cellular waste, contributing to the maintenance of cellular health and stress response pathways RAB28 also plays a role in regulating the dynamics of endocytosis and exocytosis, which are necessary for the uptake of extracellular material and the release of internalized molecules RAB28’s dysfunction is associated with neurodegenerative diseases, where impaired vesicular trafficking contributes to the accumulation of damaged proteins and organelles Moreover, RAB28 is involved in regulating processes like cell migration, differentiation, and the immune response, which links it to the development of cancer, inflammatory diseases, and other disorders where abnormal cellular dynamics occur
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