Ras-Related Protein Rab-1A (RAB1A) Antibody (ATTO390)
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Description
Ras-Related Protein Rab-1A (RAB1A) Antibody (ATTO390) is a mouse monoclonal antibody conjugated to ATTO390 for the detection of Ras-Related Protein Rab-1A (RAB1A).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-Related Protein Rab-1A (RAB1A) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | ATTO390 |
| Isotype | IgG1 |
| Purification | Purified by Protein G. |
| Size 1 | 100 µg |
| Tested Applications | WB, IP |
| Buffer | PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P62820 |
| Gene ID | 5861 |
| NCBI Accession | NP_004152.1 |
| Alias | RAB1,YPT1,Ras-related protein Rab-1A,YPT1-related protein |
| Background | Antibody anti-RAB1A |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
RAB1A, member RAS oncogene family (RAB1A) is a small GTPase that is part of the RAS superfamily, which is involved in regulating intracellular vesicular trafficking, including the transport of proteins and lipids between cellular compartments RAB1A controls the transport of materials from the endoplasmic reticulum (ER) to the Golgi apparatus, which is crucial for protein sorting and secretion Additionally, RAB1A plays a role in regulating cellular processes such as cell proliferation, division, and apoptosis through its involvement in vesicle formation and membrane dynamics Dysregulation of RAB1A can lead to a range of diseases, including cancer, where its aberrant activity contributes to uncontrolled cell growth and metastasis Furthermore, RAB1A has been linked to diseases involving defects in protein trafficking, such as neurodegenerative diseases, highlighting its importance in both normal cellular functions and disease pathogenesis
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