Ras-Related Protein Rab-1A (RAB1A) Antibody
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935106861
info@markelab.com
Precio
169€ (20 µg)
Antibody anti-RAB1A
proveedor
Abbexareference
abx110166Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Ras-related protein Rab-1A Antibody is a Rabbit Polyclonal antibody against Ras-related protein Rab-1A.
Background
RAB1A, member RAS oncogene family (RAB1A) is a small GTPase that is part of the RAS superfamily, which is involved in regulating intracellular vesicular trafficking, including the transport of proteins and lipids between cellular compartments RAB1A controls the transport of materials from the endoplasmic reticulum (ER) to the Golgi apparatus, which is crucial for protein sorting and secretion Additionally, RAB1A plays a role in regulating cellular processes such as cell proliferation, division, and apoptosis through its involvement in vesicle formation and membrane dynamics Dysregulation of RAB1A can lead to a range of diseases, including cancer, where its aberrant activity contributes to uncontrolled cell growth and metastasis Furthermore, RAB1A has been linked to diseases involving defects in protein trafficking, such as neurodegenerative diseases, highlighting its importance in both normal cellular functions and disease pathogenesis
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Ras-Related Protein Rab-1A (RAB1A)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purity
> 95%
purification
Purified by Protein G.
recommended dilution
WB: 1/1000 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
RAB1A
dry ice
No
availability
Shipped within 5-10 working days.
alias
RAB1,YPT1,Ras-related protein Rab-1A,YPT1-related protein
uniprot id
NCBI accession
NP_004152.1, NM_004161.4
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