Ras-Related Protein Rab-19 (RAB19) Antibody

Background

RAB19, member RAS oncogene family (RAB19) is a member of the RAB family of small GTPases that are involved in regulating intracellular vesicular trafficking and the movement of proteins and lipids between cellular compartments RAB19 has been shown to participate in endocytic processes, particularly in the sorting and recycling of internalized receptors, as well as in the maintenance of cellular protein homeostasis It is involved in the regulation of cell surface receptor trafficking, ensuring the appropriate recycling and degradation of internalized proteins to maintain proper cellular signaling pathways Additionally, RAB19 contributes to the regulation of the actin cytoskeleton, which is crucial for cell migration, adhesion, and polarity RAB19’s dysfunction has been linked to a variety of diseases, including cancer, where impaired vesicular trafficking can promote tumor progression by affecting the mobility and signaling of cell surface receptors Furthermore, RAB19 is also implicated in immune responses, where it plays a role in the trafficking of immune receptors and other components involved in inflammation and cell signaling