Ras-Related Protein Rab-15 (RAB15) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Ras-Related Protein Rab-15 (RAB15) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx029052
tested applications
ELISA, WB
Description
RAB15 may act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal (By similarity).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-Related Protein Rab-15 (RAB15) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P59190 |
| Alias | Ras-related protein Rab-15 |
| Background | Antibody anti-RAB15 |
| Status | RUO |
Descripción
RAB15, member RAS oncogene family (RAB15) is a member of the RAB family of small GTPases that regulate intracellular vesicular trafficking RAB15 has been shown to participate in processes related to vesicle recycling, especially in the transport and sorting of proteins and lipids within cells This protein plays a role in maintaining cellular homeostasis by ensuring the efficient movement of internalized material from early endosomes to the recycling pathway It is involved in regulating the distribution of cell surface receptors and maintaining proper receptor levels, which are important for signaling pathways related to growth, differentiation, and immune response RAB15 also impacts the trafficking of synaptic vesicles, contributing to neurotransmitter release and the proper functioning of synapses in neurons Dysregulation in RAB15’s activity has been linked to cellular dysfunction in diseases such as cancer and neurodegenerative disorders, where impaired vesicular trafficking contributes to tumor progression, synaptic failure, and the accumulation of cellular debris
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