Ras-Related Protein Rab-14 (RAB14) Antibody
357.5€ (100 µg)
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935106861
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name
Ras-Related Protein Rab-14 (RAB14) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx036226
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the RAB14 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras-Related Protein Rab-14 (RAB14) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | FBP,RAB-14,Ras-related protein Rab-14 |
| Background | Antibody anti-RAB14 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
RAB14, member RAS oncogene family (RAB14) is another GTPase that regulates vesicle trafficking, particularly in the movement of vesicles between endosomes and the plasma membrane RAB14 is involved in processes such as the recycling of internalized receptors, which is important for maintaining proper cell surface protein levels and ensuring efficient signaling pathways It also plays a role in regulating endosome dynamics and sorting, contributing to the proper functioning of lysosomes and autophagy pathways RAB14 has been shown to be important for cell adhesion and migration, as it influences the transport of integrins and other key membrane proteins involved in these processes Additionally, RAB14 is implicated in regulating immune cell function, where it contributes to the trafficking of immune receptors and cytokines, playing a role in inflammation and immune responses Dysregulation of RAB14 is associated with several diseases, including cancer, where altered vesicular trafficking can contribute to tumor metastasis and resistance to treatment Further, RAB14’s role in vesicular transport and receptor recycling makes it a significant factor in cellular homeostasis and the regulation of various signaling pathways
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