Ras GTPase-Activating Protein 1 (RASA1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Ras P21 Protein Activator (Gtpase Activating Protein) 1 Antibody is a Rabbit Polyclonal antibody against Ras P21 Protein Activator (Gtpase Activating Protein) 1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ras GTPase-Activating Protein 1 (RASA1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20936 |
| Gene ID | 5921 |
| NCBI Accession | NP_002881.1, NM_002890.2, NP_072179.1, NM_022650.2 |
| OMIM | 139150 |
| Background | Antibody anti-RASA1 |
| Status | RUO |
Descripción
Related Products
RASA1 antibody
Inhibitory regulator of the Ras-cyclic AMP pathway. Stimulates the GTPase of normal but not oncogenic Ras p21; this stimulation may be further increased in the presence of NCK1.
Ver Producto
Ras GTPase-Activating Protein 1 (RASA1) Antibody
RASA1 Antibody is a Rabbit Polyclonal antibody against RASA1. The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues. [provided by RefSeq, May 2012].
Ver Producto
Ras GTPase-Activating Protein 1 (RASA1) Antibody
Ras P21 Protein Activator (Gtpase Activating Protein) 1 Antibody is a Rabbit Polyclonal antibody against Ras P21 Protein Activator (Gtpase Activating Protein) 1.
Ver Producto