Ran GTPase-Activating Protein 1 (RANGAP1) Antibody
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935106861
info@markelab.com
Precio
292.5€ (80 µl)
Antibody anti-RANGAP1
proveedor
Abbexareference
abx027599Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1, 000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Ran GTPase-Activating Protein 1 (RANGAP1)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purification
Purified through a protein A column, followed by peptide affinity purification.
recommended dilution
WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
RANGAP1
dry ice
No
availability
Shipped within 5-10 working days.
uniprot id
NCBI accession
NP_002874.1
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proveedor
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proveedor
Abbexareference
abx004121Tested Applications
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PolyclonalRANGAP1 Antibody is a Rabbit Polyclonal antibody against RANGAP1. This gene encodes a protein that associates with the n...
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proveedor
Abbexareference
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ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalRanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over...
292.5€ (80 µl)
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