RAD50 antibody

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935106861
info@markelab.com
name
RAD50 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10634
tested applications
ELISA, WB, IHC

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
RAD50 homolog (RAD50)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200
Clonality
polyclonal
Isotype
IgG
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q92878
Alias
DNA repair protein RAD50, hRad50, RAD50, RAD50 2, RAD50 homolog
Background
Antibody anti-RAD50
Status
RUO
Note
Mol. Weight 160 kDa

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RAD50 Antibody is a Rabbit Polyclonal antibody against RAD50. The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.

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