Rabbit Vascular Endothelial Growth Factor C (VEGFC) Protein

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935106861
info@markelab.com
Precio
455€ (50 µg)
Protein VEGFC
proveedor
Abbexareference
abx168622Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Rabbit Vascular Endothelial Growth Factor C Protein is a recombinant Rabbit protein produced in a Prokaryotic expression system (E. coli).
Background
VEGFC is primarily responsible for lymphangiogenesis, the formation of lymphatic vessels, by binding to VEGFR-3 on lymphatic endothelial cells During embryonic development and tissue repair, VEGFC promotes the sprouting and maturation of lymphatic vessels VEGFC also activates VEGFR-2 in certain contexts, contributing to angiogenesis and vascular remodeling VEGFC plays a significant role in pathological processes, including cancer metastasis, where it enhances lymphatic vessel growth and facilitates tumor cell dissemination via the lymphatic system Overexpression of VEGFC is observed in various cancers such as breast cancer, melanoma, and prostate cancer, correlating with lymph node metastasis Targeting VEGFC signaling is a promising strategy to inhibit lymphangiogenesis and reduce cancer spread while maintaining tissue fluid balance and immune cell trafficking
Características del producto
category
Proteins and Peptides
origin
Rabbit
host
E. coli
immunogen target
Vascular Endothelial Growth Factor C (VEGFC)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
50 µg
size 2
100 µg
size 3
200 µg
size 4
500 µg
size 5
1 mg
observerd MW
Molecular Weight: Calculated MW: 43.1 kDa Observed MW (SDS-PAGE): 43 kDa Concentration: Prior to lyophilization: 150 µg/ml Sequence Fragment: Ala111-Arg226 Tag: N-terminal His tag and GST tag
expression
Recombinant
purity
> 80%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
VEGFC
dry ice
No
availability
Shipped within 5-7 working days.
alias
VRP,Flt4-L,LMPH1D,LMPHM4,Vascular endothelial growth factor-related protein
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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