Rabbit Vascular Endothelial Growth Factor C (VEGFC) Protein

Este producto es parte de VEGFC - Vascular Endothelial Growth Factor C
Rabbit Vascular Endothelial Growth Factor C (VEGFC) Protein

Pida mas información

935106861

info@markelab.com

Precio

455€ (50 µg)

Protein VEGFC

proveedor

Abbexa

reference

abx168622

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rabbit Vascular Endothelial Growth Factor C Protein is a recombinant Rabbit protein produced in a Prokaryotic expression system (E. coli).


Background

VEGFC is primarily responsible for lymphangiogenesis, the formation of lymphatic vessels, by binding to VEGFR-3 on lymphatic endothelial cells During embryonic development and tissue repair, VEGFC promotes the sprouting and maturation of lymphatic vessels VEGFC also activates VEGFR-2 in certain contexts, contributing to angiogenesis and vascular remodeling VEGFC plays a significant role in pathological processes, including cancer metastasis, where it enhances lymphatic vessel growth and facilitates tumor cell dissemination via the lymphatic system Overexpression of VEGFC is observed in various cancers such as breast cancer, melanoma, and prostate cancer, correlating with lymph node metastasis Targeting VEGFC signaling is a promising strategy to inhibit lymphangiogenesis and reduce cancer spread while maintaining tissue fluid balance and immune cell trafficking

Características del producto

category

Proteins and Peptides


origin

Rabbit


host

E. coli


immunogen target

Vascular Endothelial Growth Factor C (VEGFC)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

50 µg


size 2

100 µg


size 3

200 µg


size 4

500 µg


size 5

1 mg


observerd MW

Molecular Weight: Calculated MW: 43.1 kDa Observed MW (SDS-PAGE): 43 kDa Concentration: Prior to lyophilization: 150 µg/ml Sequence Fragment: Ala111-Arg226 Tag: N-terminal His tag and GST tag


expression

Recombinant


purity

> 80%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

VEGFC


dry ice

No


availability

Shipped within 5-7 working days.


alias

VRP,Flt4-L,LMPH1D,LMPHM4,Vascular endothelial growth factor-related protein


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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