Recombinant Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) is a recombinant Rabbit protein produced in E. coli using Prokaryotic expression.
Vascular cell adhesion protein 1, also known as vascular cell adhesion molecule 1 (VCAM-1) or cluster of differentiation 106 (CD106), is a human protein encoded by the VCAM1 gene. VCAM-1 plays a critical role in interacting with the integrin very late antigen-4 (VLA4).VCAM-1 is responsible for facilitating the adhesion of various immune cells, including lymphocytes, monocytes, eosinophils, and basophils, to the endothelial blood vessel. Additionally, it plays a vital role in signal transduction between leukocytes and endothelial cells, and it has been implicated in the development of conditions such as atherosclerosis and rheumatoid arthritis. Ectodomain release of VCAM-1 is observed in various situations and is often mediated by enzymes like matrix metalloproteinases (MMPs) and ADAMs (A Disintegrin and Metalloproteinase). This release can be triggered by external factors such as calcium ionophores, cytokines, and growth factors. VCAM-1 is also known by the alias CD106
Proteins and Peptides
Rabbit
E. coli
Vascular Cell Adhesion Molecule 1 (VCAM1)
E. coli
Unconjugated
Lyophilized
WB, SDS-PAGE
50 µg
100 µg
200 µg
1 mg
5 mg
> 95%
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
VCAM1
No
Shipped within 5-12 working days.
V-CAM 1,VCAM-1,INCAM-100,CD106
This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.
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