Rabbit Leptin (LEP) ELISA Kit

Este producto es parte de LEP - LEPTIN
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702€ (96 tests)

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935106861
info@markelab.com
name
Rabbit Leptin (LEP) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx155080
tested applications
ELISA

Description

Rabbit Leptin (LEP) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rabbit Leptin concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Leptin (LEP)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Leptin (LEP)
Reactivity
Rabbit
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
31.2 pg/ml - 2000 pg/ml
Sensitivity
< 11.8 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
OB,OBS,LEPD,Obese protein,Obesity factor
Background
Elisa kits for LEP
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Leptin ( LEP) is an adipokine predominantly produced by adipocytes that plays a key role in regulating energy balance, appetite, and metabolism by acting on the hypothalamus Leptin signals through its receptor (LEPR) to suppress food intake and promote energy expenditure, maintaining body weight homeostasis Circulating leptin levels are proportional to fat mass, with increased levels observed in obesity due to leptin resistance Dysregulation of leptin signaling is associated with metabolic syndrome, type 2 diabetes, and cardiovascular diseases Leptin also exerts immunomodulatory functions, influencing the activity of T cells, macrophages, and other immune cells to enhance pro-inflammatory responses It is implicated in autoimmune diseases, including rheumatoid arthritis and lupus, where elevated leptin promotes chronic inflammation Leptin’s role extends to bone metabolism, reproductive function, and wound healing, highlighting its pleiotropic effects in energy homeostasis and systemic physiology

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