Rabbit Interleukin 15 (IL15) Protein

Este producto es parte de IL15 - interleukin 15
Rabbit Interleukin 15 (IL15) Protein

Pida mas información

935106861

info@markelab.com

Precio

442€ (50 µg)

Protein IL15

proveedor

Abbexa

reference

abx067451

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Rabbit Interleukin 15 (IL15) is a recombinant Rabbit protein produced in a Prokaryotic expression system (E. coli).


Background

Interleukin 15 (IL15) is a pro-inflammatory cytokine that plays a crucial role in regulating innate and adaptive immune responses, particularly by supporting the development, activation, and survival of natural killer (NK) cells and CD8+ T cells. IL-15 is essential for immune surveillance and protection against viral infections and tumors, making it an important cytokine in both immunity and immunotherapy. IL-15 was first identified as a T-cell growth factor similar to IL-2, but it is now recognized as a distinct cytokine with a unique biological role. It is expressed by a wide range of cell types, including monocytes, macrophages, dendritic cells, epithelial cells, and fibroblasts, in response to various inflammatory stimuli. Unlike many cytokines that are secreted and act in an autocrine or paracrine fashion, IL-15 primarily functions through a unique mechanism called trans-presentation, where it binds to its receptor on neighboring cells via cell-cell contact, thus delivering potent activation signals.

Características del producto

category

Proteins and Peptides


origin

Rabbit


host

E. coli


immunogen target

Interleukin 15 (IL15)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

50 µg


size 2

100 µg


size 3

200 µg


size 4

500 µg


size 5

1 mg


observerd MW

Molecular Weight: Calculated MW: 14.3 kDa Observed MW (SDS-PAGE): 14 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asn49-Pro162 Tag: N-terminal His tag


expression

Recombinant


purity

> 97%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

IL15


dry ice

No


availability

Shipped within 5-7 working days.


alias

IL-15


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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