Rabbit Intercellular Adhesion Molecule 1 (ICAM1) Peptide (OVA)
442€ (100 µg)
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Name
Rabbit Intercellular Adhesion Molecule 1 (ICAM1) Peptide (OVA)
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx651252
Tested Applications
WB, SDS-PAGE
Description
Intercellular Adhesion Molecule 1 Peptide (OVA) is a Rabbit protein conjugated to OVA.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Intercellular Adhesion Molecule 1 (ICAM1) |
| Host | Synthetic |
| Assay Type | Activity: Not tested Sequence Fragment: Tyr504-Lys517 |
| Origin | Rabbit |
| Conjugation | OVA |
| Expression | Synthetic |
| Purity | > 90% |
| Size 1 | 100 µg |
| Size 2 | 200 µg |
| Size 3 | 500 µg |
| Size 4 | 1 mg |
| Size 5 | 5 mg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | U3KPG6 |
| Alias | BB2,CD54,P3.58,ICAM-1 |
| Background | Protein ICAM1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
Intercellular Adhesion Molecule 1 (ICAM-1) is a protein encoded by the ICAM1 gene in humans. It plays a crucial role in the immune response by aiding in the adhesion of leukocytes to the endothelial cells lining blood vessels. ICAM-1. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor for entry into respiratory epithelium. ICAM-1 is a transmembrane protein possessing an amino-terminus extracellular domain, a single transmembrane domain, and a carboxy-terminus cytoplasmic domain. The structure of ICAM-1 is characterized by heavy glycosylation, and the protein’s extracellular domain is composed of multiple loops created by disulfide bridges within the protein. ICAM-1 is important for the process of leukocyte extravasation, which is how white blood cells move from the bloodstream to infected or injured tissues. It helps leukocytes stick to endothelial cells, a crucial step in the inflammatory response. ICAM-1 can also trigger intracellular signaling events when it binds to its ligands, influencing cellular processes related to inflammation and immune responses.
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