Rabbit Intercellular Adhesion Molecule 1 (ICAM1) ELISA Kit

Este producto es parte de ICAM1 - Intercellular adhesion molecule 1
Rabbit Intercellular Adhesion Molecule 1 (ICAM1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

675€ (96 tests)

Elisa Kits ICAM1

proveedor

Abbexa

reference

abx155064

Tested Applications

ELISA

reactivity

Rabbit

status

RUO

clonality

Descripción

Rabbit Intercellular Adhesion Molecule 1 (ICAM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rabbit Intercellular Adhesion Molecule 1 (ICAM1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Intercellular Adhesion Molecule 1No significant cross-reactivity or interference between Intercellular Adhesion Molecule 1 and analogues was observed.


Background

Intercellular Adhesion Molecule 1 (ICAM-1) is a protein encoded by the ICAM1 gene in humans. It plays a crucial role in the immune response by aiding in the adhesion of leukocytes to the endothelial cells lining blood vessels. ICAM-1. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor for entry into respiratory epithelium. ICAM-1 is a transmembrane protein possessing an amino-terminus extracellular domain, a single transmembrane domain, and a carboxy-terminus cytoplasmic domain. The structure of ICAM-1 is characterized by heavy glycosylation, and the protein’s extracellular domain is composed of multiple loops created by disulfide bridges within the protein. ICAM-1 is important for the process of leukocyte extravasation, which is how white blood cells move from the bloodstream to infected or injured tissues. It helps leukocytes stick to endothelial cells, a crucial step in the inflammatory response. ICAM-1 can also trigger intracellular signaling events when it binds to its ligands, influencing cellular processes related to inflammation and immune responses.

Características del producto

category

ELISA Kits


immunogen target

Intercellular Adhesion Molecule 1 (ICAM1)


reactivity

Rabbit


test range

6.25 pg/ml - 400 pg/ml


sensitivity

< 2.53 pg/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

BB2,CD54,P3.58,ICAM-1


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

ICAM1


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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