RAB6C, Member RAS Oncogene Family (RAB6C) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
RAB6C, Member RAS Oncogene Family (RAB6C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx014801
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against RAB6C protein. Immunogen region is Internal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB6C, Member RAS Oncogene Family (RAB6C) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/40000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H0N0 |
| Alias | WTH3,Rab6-like protein WTH3,Ras-related protein Rab-6C |
| Background | Antibody anti-RAB6C |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
RAB6C, member RAS oncogene family (RAB6C) shares significant functional overlap with RAB6B and is involved in similar roles in vesicular trafficking, protein sorting, and cell signaling RAB6C regulates the transport of vesicles from the Golgi to the plasma membrane and is crucial for maintaining cellular structure and membrane dynamics It is involved in cellular processes such as exocytosis, receptor recycling, and secretion of proteins involved in immune response and tissue remodeling Disruption of RAB6C can lead to defects in cell growth, signaling, and cellular organization, contributing to diseases such as cancer, where aberrant vesicle trafficking influences tumorigenesis RAB6C has also been implicated in neurodegenerative diseases, where alterations in vesicular trafficking disrupt neuronal function and lead to cellular dysfunction In addition to these roles, RAB6C is important for maintaining the integrity of cellular compartments involved in endosomal trafficking
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