RAB5C, Member RAS Oncogene Family (RAB5C) Antibody
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935106861
info@markelab.com
Precio
169€ (20 µl)
Antibody anti-RAB5C
proveedor
Abbexareference
abx320911Tested Applications
ELISA, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
RAB5C Antibody is a Rabbit Polyclonal against RAB5C.
Background
RAB5C, member RAS oncogene family (RAB5C) is closely related to RAB5B and has similar functions in regulating early endosomal trafficking and vesicle fusion RAB5C participates in receptor-mediated endocytosis, controlling the internalization and sorting of membrane proteins for recycling or degradation It plays an essential role in maintaining cellular membrane dynamics and the regulation of the Golgi apparatus and lysosomal functions RAB5C is also involved in the modulation of cell signaling pathways, particularly those related to growth factor receptors and tyrosine kinase signaling Its dysfunction is associated with disorders involving defective cellular trafficking, including cancer, where disruptions in vesicular transport may promote tumor progression and drug resistance In addition, RAB5C is involved in regulating the immune response, with potential implications in immune cell trafficking and receptor regulation
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
RAB5C, Member RAS Oncogene Family (RAB5C)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, IHC
purification
Antigen Affinity Chromatography.
recommended dilution
IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
size 1
20 µl
size 2
50 µl
size 3
100 µl
size 4
200 µl
size 5
1 ml
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
RAB5C
dry ice
No
availability
Shipped within 5-10 working days.
alias
RABL,L1880,RAB5L,RAB5CL,Ras-related protein Rab-5C
uniprot id
NCBI accession
NP_001238968.1, NM_001252039.1, NP_004574.2, NM_004583.3
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