RAB5C, Member RAS Oncogene Family (RAB5C) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
RAB5C, Member RAS Oncogene Family (RAB5C) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx119126
tested applications
WB
Description
RAB5C Antibody is a Rabbit Polyclonal antibody against RAB5C.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB5C, Member RAS Oncogene Family (RAB5C) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P51148 |
| Alias | RABL,L1880,RAB5L,RAB5CL,Ras-related protein Rab-5C |
| Background | Antibody anti-RAB5C |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
RAB5C, member RAS oncogene family (RAB5C) is closely related to RAB5B and has similar functions in regulating early endosomal trafficking and vesicle fusion RAB5C participates in receptor-mediated endocytosis, controlling the internalization and sorting of membrane proteins for recycling or degradation It plays an essential role in maintaining cellular membrane dynamics and the regulation of the Golgi apparatus and lysosomal functions RAB5C is also involved in the modulation of cell signaling pathways, particularly those related to growth factor receptors and tyrosine kinase signaling Its dysfunction is associated with disorders involving defective cellular trafficking, including cancer, where disruptions in vesicular transport may promote tumor progression and drug resistance In addition, RAB5C is involved in regulating the immune response, with potential implications in immune cell trafficking and receptor regulation
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