RAB41, Member RAS Oncogene Family (RAB41) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
RAB41, Member RAS Oncogene Family (RAB41) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx237035
tested applications
ELISA, WB
Description
RAB41 Antibody is a Rabbit Polyclonal against RAB41.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB41, Member RAS Oncogene Family (RAB41) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5JT25 |
| Gene ID | 347517 |
| Alias | Ras-related protein Rab-41 |
| Background | Antibody anti-RAB41 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
RAB41, member RAS oncogene family (RAB41) is a member of the RAB family of GTPases and is involved in regulating intracellular vesicle trafficking. RAB41 specifically contributes to the movement of vesicles in endocytic and exocytic pathways, playing a key role in maintaining cellular membrane dynamics and protein sorting. This protein is essential for the proper function of synaptic vesicles in neurons, facilitating the recycling of neurotransmitter receptors and the regulation of synaptic vesicle release. RAB41 is also involved in the trafficking of endosomal compartments, where it helps sort proteins for degradation or recycling. Its function in receptor trafficking is critical for cellular responsiveness to external stimuli and for maintaining receptor homeostasis. RAB41 has been implicated in various diseases due to its role in endocytosis and receptor signaling, including neurodegenerative conditions where impaired receptor recycling and vesicular trafficking contribute to synaptic dysfunction. Moreover, its involvement in cellular stress response pathways suggests that RAB41 may play a protective role in defending against cellular damage.
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