RAB41 antibody
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935106861
info@markelab.com
name
RAB41 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07035
tested applications
ELISA, WB
Description
Required for normal Golgi ribbon organization and ER-to-Golgi trafficking.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB41, member RAS oncogene family (RAB41) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 25 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q5JT25 |
| Gene ID | 347517 |
| Alias | Ras-related protein Rab-41 |
| Background | Antibody anti-RAB41 |
| Status | RUO |
| Note | Mol. Weight 25 kDa |
Descripción
RAB41, member RAS oncogene family (RAB41) is a member of the RAB family of GTPases and is involved in regulating intracellular vesicle trafficking. RAB41 specifically contributes to the movement of vesicles in endocytic and exocytic pathways, playing a key role in maintaining cellular membrane dynamics and protein sorting. This protein is essential for the proper function of synaptic vesicles in neurons, facilitating the recycling of neurotransmitter receptors and the regulation of synaptic vesicle release. RAB41 is also involved in the trafficking of endosomal compartments, where it helps sort proteins for degradation or recycling. Its function in receptor trafficking is critical for cellular responsiveness to external stimuli and for maintaining receptor homeostasis. RAB41 has been implicated in various diseases due to its role in endocytosis and receptor signaling, including neurodegenerative conditions where impaired receptor recycling and vesicular trafficking contribute to synaptic dysfunction. Moreover, its involvement in cellular stress response pathways suggests that RAB41 may play a protective role in defending against cellular damage.
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