RAB3B, Member RAS Oncogene Family (RAB3B) Antibody (HRP)
169€ (20 µg)
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935106861
info@markelab.com
name
RAB3B, Member RAS Oncogene Family (RAB3B) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx305020
tested applications
ELISA
Description
RAB3B Antibody (HRP) is a Rabbit Polyclonal against RAB3B conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB3B, Member RAS Oncogene Family (RAB3B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20337 |
| Gene ID | 5865 |
| OMIM | 179510 |
| Alias | Ras-related protein Rab-3B |
| Background | Antibody anti-RAB3B |
| Status | RUO |
Descripción
RAB3B, member RAS oncogene family (RAB3B) is a small GTPase that is part of the RAS superfamily, involved in regulating vesicular trafficking, membrane dynamics, and cellular signaling RAB3B is particularly important in the release of neurotransmitters and hormones, as it plays a key role in synaptic vesicle recycling and exocytosis In neurons, RAB3B helps control the fusion of synaptic vesicles with the plasma membrane, allowing for neurotransmitter release and communication between nerve cells Similarly, RAB3B is involved in hormone secretion, such as insulin release in pancreatic beta cells Its dysregulation can lead to neurological disorders, including epilepsy, and endocrine disorders such as diabetes, where improper vesicular trafficking impairs neurotransmitter and hormone release Furthermore, RAB3B has been linked to some types of cancer, where its abnormal activity may contribute to tumorigenesis and metastasis due to altered vesicular dynamics
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