RAB3B antibody
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935106861
info@markelab.com
name
RAB3B antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07026
tested applications
ELISA, WB, IHC, FC, IF
Description
Protein transport. Probably involved in vesicular traffic(By similarity).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB3B, member RAS oncogene family (RAB3B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 25 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, FC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P20337 |
| Gene ID | 5865 |
| Alias | Ras-related protein Rab-3B |
| Background | Antibody anti-RAB3B |
| Status | RUO |
| Note | Mol. Weight 25 kDa |
Descripción
RAB3B, member RAS oncogene family (RAB3B) is a small GTPase that is part of the RAS superfamily, involved in regulating vesicular trafficking, membrane dynamics, and cellular signaling RAB3B is particularly important in the release of neurotransmitters and hormones, as it plays a key role in synaptic vesicle recycling and exocytosis In neurons, RAB3B helps control the fusion of synaptic vesicles with the plasma membrane, allowing for neurotransmitter release and communication between nerve cells Similarly, RAB3B is involved in hormone secretion, such as insulin release in pancreatic beta cells Its dysregulation can lead to neurological disorders, including epilepsy, and endocrine disorders such as diabetes, where improper vesicular trafficking impairs neurotransmitter and hormone release Furthermore, RAB3B has been linked to some types of cancer, where its abnormal activity may contribute to tumorigenesis and metastasis due to altered vesicular dynamics
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