Human Ras-Related Protein Rab-3B (RAB3B) Protein
234€ (5 µg)
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935106861
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name
Human Ras-Related Protein Rab-3B (RAB3B) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx261461
tested applications
SDS-PAGE
Description
Ras-Related Protein Rab-3B (RAB3B) is a recombinant protein consisting of a single, non-glycosylated polypeptide chain containing 239 amino acids, expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Ras-Related Protein Rab-3B (RAB3B) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: 1-219 AA. Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | 26.9 kDa |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE). <br> Sterile filtered. |
| Purification | Purified by proprietary chromatography techniques. |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Buffer | 20 mM Tris-HCl, pH 8.0, containing 0.1 M NaCl, 2 mM DTT and 20% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Store at 4°C for up to 4 weeks. Store at -20 °C for long term storage. For long term storage, it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20337 |
| Alias | Ras-related protein Rab-3B |
| Background | Protein RAB3B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Concentration: 0.5 mg/ml |
Descripción
RAB3B, member RAS oncogene family (RAB3B) is a small GTPase that is part of the RAS superfamily, involved in regulating vesicular trafficking, membrane dynamics, and cellular signaling RAB3B is particularly important in the release of neurotransmitters and hormones, as it plays a key role in synaptic vesicle recycling and exocytosis In neurons, RAB3B helps control the fusion of synaptic vesicles with the plasma membrane, allowing for neurotransmitter release and communication between nerve cells Similarly, RAB3B is involved in hormone secretion, such as insulin release in pancreatic beta cells Its dysregulation can lead to neurological disorders, including epilepsy, and endocrine disorders such as diabetes, where improper vesicular trafficking impairs neurotransmitter and hormone release Furthermore, RAB3B has been linked to some types of cancer, where its abnormal activity may contribute to tumorigenesis and metastasis due to altered vesicular dynamics
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