RAB38, Member RAS Oncogene Family (RAB38) Antibody
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Description
Rabbit Polyclonal against the RAB38 protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB38, Member RAS Oncogene Family (RAB38) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | BC015808 |
| Alias | rrGTPbp,NY-MEL-1,Melanoma antigen NY-MEL-1,Ras-related protein Rab-38 |
| Background | Antibody anti-RAB38 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
RAB38, member RAS oncogene family (RAB38) is involved in regulating vesicular trafficking, with a primary focus on the sorting and delivery of cargo proteins within the secretory pathway It plays a key role in the movement of vesicles from the Golgi apparatus to other cellular compartments such as the plasma membrane or lysosomes, which are essential for proper cell function and membrane recycling RAB38 is involved in the maintenance of cell signaling by regulating the trafficking of receptor proteins and enzymes, ensuring their correct localization and function Additionally, RAB38 participates in autophagy, a critical cellular process for degrading and recycling cellular components RAB38’s dysfunction is associated with disorders related to impaired vesicular trafficking, including certain types of cancer and neurodegenerative diseases where disturbed cellular function contributes to pathological changes
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