RAB33A, Member RAS Oncogene Family (RAB33A) Antibody

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221€ (50 µg)

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935106861
info@markelab.com
name
RAB33A, Member RAS Oncogene Family (RAB33A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx327647
tested applications
ELISA, WB

Description

RAB33A Antibody is a Rabbit Polyclonal against RAB33A.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
RAB33A, Member RAS Oncogene Family (RAB33A)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1/20000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q14088
Gene ID
9363
Alias
RabS10,Small GTP-binding protein S10,Ras-related protein Rab-33A
Background
Antibody anti-RAB33A
Status
RUO

Descripción

RAB33A, member RAS oncogene family (RAB33A) is involved in regulating vesicle transport and the movement of proteins and lipids between the Golgi apparatus, endosomes, and plasma membrane RAB33A plays a crucial role in intracellular membrane trafficking, ensuring the proper sorting, recycling, and delivery of cellular components to their destinations It is particularly important for the regulation of autophagy, where it contributes to the formation and maturation of autophagosomes, which are essential for degrading and recycling damaged cellular material Additionally, RAB33A is implicated in controlling the dynamics of endocytosis, a key process for the uptake of extracellular molecules into the cell, and exocytosis, which is the release of molecules from the cell via vesicular fusion RAB33A’s role in these processes links it to various cellular functions, including signal transduction, cell migration, and immune responses RAB33A’s dysfunction has been linked to disorders such as neurodegenerative diseases and cancer, where altered trafficking processes lead to cellular dysfunction, loss of homeostasis, and abnormal growth

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