RAB33A antibody

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935106861
info@markelab.com
name
RAB33A antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07017
tested applications
ELISA, WB, IHC

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
RAB33A, member RAS oncogene family (RAB33A)
Host
Rabbit
Reactivity
Human, Mouse
Recommended Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
27 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
Q14088
Gene ID
9363
Alias
RabS10,Small GTP-binding protein S10,Ras-related protein Rab-33A
Background
Antibody anti-RAB33A
Status
RUO
Note
Mol. Weight 27 kDa

RAB33A, member RAS oncogene family (RAB33A) is involved in regulating vesicle transport and the movement of proteins and lipids between the Golgi apparatus, endosomes, and plasma membrane RAB33A plays a crucial role in intracellular membrane trafficking, ensuring the proper sorting, recycling, and delivery of cellular components to their destinations It is particularly important for the regulation of autophagy, where it contributes to the formation and maturation of autophagosomes, which are essential for degrading and recycling damaged cellular material Additionally, RAB33A is implicated in controlling the dynamics of endocytosis, a key process for the uptake of extracellular molecules into the cell, and exocytosis, which is the release of molecules from the cell via vesicular fusion RAB33A’s role in these processes links it to various cellular functions, including signal transduction, cell migration, and immune responses RAB33A’s dysfunction has been linked to disorders such as neurodegenerative diseases and cancer, where altered trafficking processes lead to cellular dysfunction, loss of homeostasis, and abnormal growth

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