RAB2B, Member RAS Oncogene Family (RAB2B) Antibody
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Pida mas información
935106861
info@markelab.com
Precio
292.5€ (80 µl)
Antibody anti-RAB2B
proveedor
Abbexareference
abx029877Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM].
Background
RAB2B, member RAS oncogene family (RAB2B) is another GTPase closely related to RAB2A and involved in regulating vesicular trafficking and cellular transport RAB2B plays a crucial role in the movement of vesicles between the ER and Golgi apparatus, facilitating the trafficking of proteins and lipids to their correct cellular destinations In addition to its role in protein secretion, RAB2B is involved in regulating Golgi organization, membrane trafficking, and cell signaling Disruption of RAB2B has been linked to various diseases, including cancer and metabolic disorders, where changes in vesicle trafficking and cellular communication contribute to uncontrolled cell growth and aberrant metabolism Additionally, RAB2B is involved in cellular responses to oxidative stress and can affect the cell's ability to maintain homeostasis under adverse conditions, making it an important factor in both health and disease
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
RAB2B, Member RAS Oncogene Family (RAB2B)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified through a protein A column, followed by peptide affinity purification.
recommended dilution
WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
RAB2B
dry ice
No
availability
Shipped within 5-10 working days.
alias
Ras-related protein Rab-2B
uniprot id
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proveedor
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