RAB2B, Member RAS Oncogene Family (RAB2B) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
RAB2B, Member RAS Oncogene Family (RAB2B) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx029877
tested applications
ELISA, WB
Description
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM].
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB2B, Member RAS Oncogene Family (RAB2B) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WUD1 |
| Alias | Ras-related protein Rab-2B |
| Background | Antibody anti-RAB2B |
| Status | RUO |
Descripción
RAB2B, member RAS oncogene family (RAB2B) is another GTPase closely related to RAB2A and involved in regulating vesicular trafficking and cellular transport RAB2B plays a crucial role in the movement of vesicles between the ER and Golgi apparatus, facilitating the trafficking of proteins and lipids to their correct cellular destinations In addition to its role in protein secretion, RAB2B is involved in regulating Golgi organization, membrane trafficking, and cell signaling Disruption of RAB2B has been linked to various diseases, including cancer and metabolic disorders, where changes in vesicle trafficking and cellular communication contribute to uncontrolled cell growth and aberrant metabolism Additionally, RAB2B is involved in cellular responses to oxidative stress and can affect the cell's ability to maintain homeostasis under adverse conditions, making it an important factor in both health and disease
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