RAB24, Member RAS Oncogene Family (RAB24) Antibody

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221€ (50 µg)

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935106861
info@markelab.com
name
RAB24, Member RAS Oncogene Family (RAB24) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx326461
tested applications
ELISA, IHC

Description

RAB24 Antibody is a Rabbit Polyclonal against RAB24.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
RAB24, Member RAS Oncogene Family (RAB24)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
ELISA: 1/10000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q969Q5
Gene ID
53917
Alias
Ras-related protein Rab-24
Background
Antibody anti-RAB24
Status
RUO

Descripción

RAB24, member RAS oncogene family (RAB24) is a small GTPase involved in regulating vesicular trafficking and protein sorting within cells RAB24 plays a critical role in autophagy, a process essential for maintaining cellular homeostasis by degrading and recycling damaged organelles and proteins RAB24 assists in the formation of autophagosomes and their fusion with lysosomes, enabling the degradation and recycling of cellular waste products Additionally, RAB24 is involved in regulating the trafficking of certain proteins to the lysosome, impacting the quality control of cellular proteins and the clearance of damaged components This makes RAB24 important for cellular survival and function under stress conditions such as nutrient deprivation or oxidative stress RAB24 also participates in regulating cellular responses to environmental changes and maintaining protein integrity by promoting the clearance of misfolded proteins In cancer, RAB24 has been implicated in modulating autophagic processes that influence tumor growth and metastasis by affecting cell survival pathways and resistance to chemotherapy

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