RAB24 antibody
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935106861
info@markelab.com
name
RAB24 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab07007
tested applications
ELISA, WB, IHC
Description
RAB24 is a small GTPase of the Rab subfamily of Ras-related proteins that regulate intracellular protein trafficking (Olkkonen et al., 1993 [PubMed 8126105]).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB24, member RAS oncogene family (RAB24) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 22 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q969Q5 |
| Gene ID | 53917 |
| Alias | Ras-related protein Rab-24 |
| Background | Antibody anti-RAB24 |
| Status | RUO |
| Note | Mol. Weight 22 kDa |
Descripción
RAB24, member RAS oncogene family (RAB24) is a small GTPase involved in regulating vesicular trafficking and protein sorting within cells RAB24 plays a critical role in autophagy, a process essential for maintaining cellular homeostasis by degrading and recycling damaged organelles and proteins RAB24 assists in the formation of autophagosomes and their fusion with lysosomes, enabling the degradation and recycling of cellular waste products Additionally, RAB24 is involved in regulating the trafficking of certain proteins to the lysosome, impacting the quality control of cellular proteins and the clearance of damaged components This makes RAB24 important for cellular survival and function under stress conditions such as nutrient deprivation or oxidative stress RAB24 also participates in regulating cellular responses to environmental changes and maintaining protein integrity by promoting the clearance of misfolded proteins In cancer, RAB24 has been implicated in modulating autophagic processes that influence tumor growth and metastasis by affecting cell survival pathways and resistance to chemotherapy
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