Rab23, Member Ras Oncogene Family (RAB23) Antibody
637€ (100 µl)
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Name
Rab23, Member Ras Oncogene Family (RAB23) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx114971
Tested Applications
ELISA, WB
Description
Rab23, Member Ras Oncogene Family Antibody is a Rabbit Polyclonal antibody against Rab23, Member Ras Oncogene Family.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Rab23, Member Ras Oncogene Family (RAB23) Immunogen: Human RAB23. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ULC3 |
| Gene ID | 51715 |
| OMIM | 201000 |
| Alias | HSPC137,Ras-related protein Rab-23 |
| Background | Antibody anti-RAB23 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
RAB23, member RAS oncogene family (RAB23) is a small GTPase that regulates the trafficking of intracellular vesicles and plays a role in the movement of molecules between the endosomal system and other cellular compartments, including the Golgi apparatus and plasma membrane RAB23 has been shown to participate in the process of autophagy, where it helps in the sorting and degradation of cellular materials via the lysosomal pathway, ensuring that damaged or unwanted components are properly processed and removed from the cell This function links RAB23 to cellular stress responses, maintaining cellular integrity and preventing the accumulation of damaged proteins and organelles Additionally, RAB23 is involved in regulating the function of the sonic hedgehog signaling pathway, which is critical for development and the control of cellular proliferation RAB23’s dysfunction is linked to various genetic disorders, including craniofacial malformations, where defects in its trafficking function disrupt proper cellular signaling and tissue development Furthermore, RAB23 is involved in cancer biology, where aberrant vesicular trafficking contributes to uncontrolled cell growth, tumor progression, and metastasis
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