RAB1A, Member RAS Oncogene Family (RAB1A) Antibody
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Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | RAB1A, Member RAS Oncogene Family (RAB1A) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | RAB1,YPT1,Ras-related protein Rab-1A,YPT1-related protein |
| Background | Antibody anti-RAB1A |
| Status | RUO |
Descripción
RAB1A, member RAS oncogene family (RAB1A) is a small GTPase that is part of the RAS superfamily, which is involved in regulating intracellular vesicular trafficking, including the transport of proteins and lipids between cellular compartments RAB1A controls the transport of materials from the endoplasmic reticulum (ER) to the Golgi apparatus, which is crucial for protein sorting and secretion Additionally, RAB1A plays a role in regulating cellular processes such as cell proliferation, division, and apoptosis through its involvement in vesicle formation and membrane dynamics Dysregulation of RAB1A can lead to a range of diseases, including cancer, where its aberrant activity contributes to uncontrolled cell growth and metastasis Furthermore, RAB1A has been linked to diseases involving defects in protein trafficking, such as neurodegenerative diseases, highlighting its importance in both normal cellular functions and disease pathogenesis
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