RAB1A, Member RAS Oncogene Family Protein

Background

RAB1A, member RAS oncogene family (RAB1A) is a small GTPase that is part of the RAS superfamily, which is involved in regulating intracellular vesicular trafficking, including the transport of proteins and lipids between cellular compartments RAB1A controls the transport of materials from the endoplasmic reticulum (ER) to the Golgi apparatus, which is crucial for protein sorting and secretion Additionally, RAB1A plays a role in regulating cellular processes such as cell proliferation, division, and apoptosis through its involvement in vesicle formation and membrane dynamics Dysregulation of RAB1A can lead to a range of diseases, including cancer, where its aberrant activity contributes to uncontrolled cell growth and metastasis Furthermore, RAB1A has been linked to diseases involving defects in protein trafficking, such as neurodegenerative diseases, highlighting its importance in both normal cellular functions and disease pathogenesis