Pyruvate Kinase, Liver And RBC (PKLR) Antibody

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312€ (60 µl)

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935106861
info@markelab.com
name
Pyruvate Kinase, Liver And RBC (PKLR) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001571
tested applications
WB

Description

PKLR Antibody is a Rabbit Polyclonal antibody against PKLR. The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Pyruvate Kinase, Liver And RBC (PKLR)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by affinity chromatography.
Size 1
60 µl
Size 2
120 µl
Size 3
200 µl
Form
Liquid
Tested Applications
WB
Buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P30613
Gene ID
5313
NCBI Accession
NP_000289.1
Background
Antibody anti-PKLR
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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